Search Engines Research Articles

AlphaFind: discover structure similarity across the proteome in AlphaFold DB.

AlphaFind is a web-based search engine that provides fast structure-based retrieval in the entire set of AlphaFold DB structures. Unlike other protein processing tools, AlphaFind is focused entirely on tertiary structure, automatically extracting the main 3D features of each protein chain and using a machine learning model to find the most similar structures. This indexing approach and the 3D feature extraction method used by AlphaFind have both demonstrated remarkable scalability to large datasets as well as to large protein structures. The web application itself has been designed with a focus on clarity and ease of use. The searcher accepts any valid UniProt ID, Protein Data Bank ID or gene symbol as input, and returns a set of similar protein chains from AlphaFold DB, including various similarity metrics between the query and each of the retrieved results. In addition to the main search functionality, the application provides 3D visualizations of protein structure superpositions in order to allow researchers to instantly analyze the structural similarity of the retrieved results. The AlphaFind web application is available online for free and without any registration at https://alphafind.fi.muni.cz.

Radiological insights into rheumatoid meningitis - a rare central nervous system manifestation of rheumatoid arthritis: a retrospective review of six cases.

The objective is to analyze and review the clinical, laboratory, and neuroimaging characteristics of rheumatoid meningitis (RM) in six patients with known rheumatoid arthritis (RA). We performed a retrospective review of patients diagnosed with RM from August 2012 to June 2023. To identify the cases, we used medical term search engines and the hospital´s radiology case database. Clinical information and laboratory findings were gathered from the medical records. A neuroradiologist with five years of experience reviewed and analyzed the RM to determine the characteristics findings of RM. Six patients with RM are included. Seizures along with headaches were among the clinical signs that were documented. All the patients had high levels of rheumatoid factor (RF) and anti-cyclic citrullinated peptides (ACPA) in the peripheral blood. Biopsy in two cases confirmed typical rheumatoid nodules. Leptomeningeal enhancement was found bilaterally in all cases and was predominantly found in the frontoparietal region. "Mismatch DWI/FLAIR" was found in five patients. Bilateral subdural collections could be found in two patients. Brain PET scan revealed increased metabolism in two cases. Rheumatoid meningitis is a rare complication of rheumatoid arthritis (RA) with challenging clinical diagnosis due to non-specific symptoms. This study highlights the importance of MR in detecting characteristic neuroimaging patterns, including "mismatch DWI/FLAIR", to aid in early diagnosis. Increased awareness of this condition may facilitate timely intervention and improve prognosis. These results still need to be verified by large studies.

Misinformation does not reduce trust in accurate search results, but warning banners may backfire

People rely on search engines for information in critical contexts, such as public health emergencies–but what makes people trust some search results more than others? Can search engines influence people’s levels of trust by controlling how information is presented? And, how does the presence of misinformation influence people’s trust? Research has identified both rank and the presence of misinformation as factors impacting people’s search behavior. Here, we extend these findings by measuring the effects of these factors, as well as misinformation warning banners, on the perceived trustworthiness of individual search results. We conducted three online experiments (N = 3196) using Covid-19-related queries, and found that although higher-ranked results are clicked more often, they are not more trusted. We also showed that misinformation does not damage trust in accurate results displayed below it. In contrast, while a warning about unreliable sources might decrease trust in misinformation, it significantly decreases trust in accurate information. This research alleviates some concerns about how people evaluate the credibility of information they find online, while revealing a potential backfire effect of one misinformation-prevention approach; namely, that banner warnings about source unreliability could lead to unexpected and nonoptimal outcomes in which people trust accurate information less.

Challenges and Coping Strategies in Transitioning From Caregiving to Widowhood: A Systematic Review.

Ninety-one percent of surviving spouses in the U.S. cared for their spouses before they died. This review explores the challenges of the transition from caregiving to widowhood and different coping strategies used by widowed spousal caregivers. A systematic review of literature on the transition from caregiving to widowhood was conducted using four major academic search engines. Overall, 280 articles were identified, with 22 meeting the inclusion criteria. Challenges for widowed caregivers included experiencing care burden, letting go of the caregiver role, grief, and triggers. Widowed caregivers' coping strategies included social support and services use, filling the time gap, finding spirituality, and engaging in unhealthy behaviors. Future research is needed to determine the efficacy of widowed caregivers' coping strategies. Concerted and collaborative action by health professionals, community organizations, and policymakers is needed to develop programs and other approaches to support widowed caregivers.

Evidence on the ecological and physical effects of built structures in shallow, tropical coral reefs: a systematic map

BackgroundShallow, tropical coral reefs face compounding threats from climate change, habitat degradation due to coastal development and pollution, impacts from storms and sea-level rise, and pulse disturbances like blast fishing, mining, dredging, and ship groundings that reduce reef height and complexity. One approach toward restoring coral reef physical structure from such impacts is deploying built structures of artificial, natural, or hybrid (both artificial and natural) origin. Built structures range from designed modules and repurposed materials to underwater sculptures and intentionally placed natural rocks. Restoration practitioners and coastal managers increasingly consider incorporating – and in many cases have already begun to incorporate – built structures into coral reef-related applications, yet synthesized evidence on the ecological (coral-related; e.g., coral growth, coral survival) and physical performance of built structures in coral ecosystems across a variety of contexts (e.g., restoration, coastal protection, mitigation, tourism) is not readily available to guide decisions. To help fill this gap and inform management decisions, we systematically mapped the global distribution and abundance of published evidence on the ecological (coral-related) and physical performance of built structure interventions in shallow (≤ 30 m), tropical (35°N to 35°S) coral ecosystems.MethodsTo identify potentially relevant articles, we used predefined and tested strategies to search two indexing platforms, one bibliographic database, two open discovery citation indexes, one web-based search engine, one novel literature discovery tool, 19 organizational websites, and information requested from stakeholders. Discovered articles were screened according to preset eligibility criteria first by title and abstract and second by full text. Articles included during full text screening were coded to extract metadata following a predefined framework. We analyzed and visualized the evidence base to answer our primary and secondary research questions and to identify knowledge clusters and gaps. Findings are reported in a narrative synthesis.ResultsOur search discovered > 20,000 potentially relevant unique articles, of which 258 were included in the systematic map. The evidence base spans 50 countries, and the volume of evidence increased over the past five decades. Built structures were most commonly installed for coral restoration (61%) or coastal protection (12%). Structures were predominately characterized as artificial (87%), with fewer hybrid or natural interventions. Evidence clusters existed for intentionally designed artificial structures and outcomes associated with coral-related ecological performance, including coral mortality, growth, recruitment, cover, and diversity. Pronounced evidence gaps occurred at the intersection of several ecological coral-related performance outcomes (e.g., connectivity, microbiome) across all types of built structures; gaps also existed across most ecological coral-related outcomes for artwork and repurposed artificial structures. Physical performance of built structures was most frequently evaluated for outcomes related to waves (n = 14) and sediment and morphology (n = 11) with pervasive evidence gaps across other outcomes like storm surge and water level.ConclusionsWhile the systematic map highlighted several evidence clusters, it also revealed pronounced evidence gaps surrounding the coral-related ecological and physical performance of built structures in coral ecosystems. The compiled evidence base will help inform policy, management, and future consideration of built structures in reef-related applications, including habitat restoration, environmental mitigation, and coastal protection. Map findings also point to promising future research avenues, such as investigating seascape-scale ecological effects of and the physical performance of built structures.

Media reporting of violence against children in the Eastern Mediterranean Region during the early days of COVID-19 pandemic

Background: Violence against children constitutes a significant public health problem globally. Aim: To document and compare media reports of violence against children before and during COVID-19, and measures taken by countries to address such violence. Methods: This comparative review covered news reports of violence against children from 1 January to 30 June of 2019 and 2020 in the WHO Eastern Mediterranean Region countries. A total of 823 articles published in Arabic and English, covering incidents, initiatives, opinions and views on all types of violence among children under 18 years of age were sourced using search engines and platforms and reviewed. News on incidents was analysed quantitatively while news on initiatives and opinions was analysed qualitatively. Results: Some 40.3% of the news reports was on incidents, followed by interviews or opinions (31.5%) and initiatives (28.2%). There were 1129 reports of violence against children from 1 January to 30 June of 2019 and 1880 for the same period in 2020. Reports of physical violence increased from 34% in 2019 to 40% in 2020, while reports of sexual violence decreased from 45% in 2019 to 37% in 2020. Views and opinion reports showed 0.4–1.1% alignment with the 7 INSPIRE strategies. Conclusion: The COVID-19 pandemic affected the incidence and reporting of violence against children across the region. It is essential to provide accurate and sensitive media coverage for incidences of violence against children so that survivors and at-risk children can receive adequate support and ensure that communities can tackle it appropriately

An automated information extraction system from the knowledge graph based annual financial reports

This article presents a semantic web-based solution for extracting the relevant information automatically from the annual financial reports of the banks/financial institutions and presenting this information in a queryable form through a knowledge graph. The information in these reports is significantly desired by various stakeholders for making key investment decisions. However, this information is available in an unstructured format making it much more complex and challenging to understand and query manually or even through digital systems. Another challenge that makes the understanding of information more complex is the variation of terminologies among financial reports of different banks or financial institutions. The solution presented in this article signifies an ontological approach to solving the standardization problems of the terminologies in this domain. It further addresses the issue of semantic differences to extract relevant data sharing common semantics. Such semantics are then incorporated by implementing their representation as a Knowledge Graph to make the information understandable and queryable. Our results highlight the usage of Knowledge Graph in search engines, recommender systems and question-answering (Q-A) systems. This financial knowledge graph can also be used to serve the task of financial storytelling. The proposed solution is implemented and tested on the datasets of various banks and the results are presented through answers to competency questions evaluated on precision and recall measures.

Dimensions of living with emetophobia

Purpose This paper aims to present an examination of selected literature about the lived experiences of those with emetophobia. Its intention is to inform further empirical enquiry and subsequent approaches to treatment and care aimed at inclusive support for sufferers. To that end, it is important to bring the sufferers’ narrative into public and professional domains. Design/methodology/approach A systematic search of multiple databases using the search engine Discover@bolton and grey literature was undertaken to obtain evidence about the lived experiences of people with emetophobia. The search terms used were “emetophobia” and combinations of associated topic phrases using Boolean operators (AND / OR): “Emetophobia” OR “fear of vomiting” OR “fear of being sick”, Emetophobia AND “lived experiences” and finally Emetophobia OR “fear of vomiting” OR “fear of being sick” AND “lived experiences”. Eight papers were included in the review and five items of grey literature. Findings Several themes were identified in this literature including fear, escape and avoidance, other influences, consequences and medicalisation. The findings reveal that the experiences of those with emetophobia are subsumed beneath a focus on diagnosis and treatment. When it comes to understanding the actual lived experience of a person with emetophobia, the evidence presents the reader with what treatment may work and how they might respond to it, but largely omits the voice of the individual with emetophobia. This signals a need to undertake enquiry to bring this to the fore and so inform ways of greater inclusive practice for the public and professionals alike. Research limitations/implications The evidence reviewed in this paper can be noted for the limited discussion about the individual’s lived experience of emetophobia. Gaining insight into this would contribute to raising awareness in a wider public arena and inform carers and healthcare professionals’ understanding. It would also display the importance of an individual context and health journey. Practical implications Knowing this can inform approaches to helping an individual either to live with the phobia and manage its impact on daily living (positive rather than maladaptive coping mechanisms) or to overcome it with or without adjunct medical treatment (if this is possible). Social implications Knowing based on contemporary empirical enquiry will inform policy and guideline development. Whatever course is taken, it must contribute to steps being taken towards achieving a better quality of life for individual sufferers. The findings of this paper likewise inform the need for further study into the individual lived experience of emetophobia. Originality/value This paper is original in having identified a need to bring empirical evidence of the lived experience of sufferers with emetophobia into the public and professional domain.

Knowledge Graph Analysis On English Wikipedia Pages Using A Deep Learning Algorithm

Analysis of social networks or online communities can be very difficult when working on large networks, as many measurements require expensive hardware. For example, identifying the community structure of a network is a very computationally expensive task. Embedded graph is a way to represent graphs with vectors, so that further analysis becomes easier. The purpose of this research is to analyze the knowledge graph from the wikipedia article data. This research aims to implement web scraping techniques on the wikipedia article search engine and display similar wikipedia pages and analyze them using a predetermined deep learning algorithm. Data collection in this research used scraping techniques to retrieve data from the unstructured wikipedia website and then processed it into structured data. The method used in this research is a standard cross-industry process for data mining by performing phases of data collection, data processing, proposed algorithms, testing and evaluation. The algorithm applied is deepwalk, kmeans, girvan newman. By doing this research, it is expected to provide knowledge about the deep learning approach for data representation of the wikipedia pages knowledge graph and can help users find similar wikipedia pages and enrich literacy on knowledge graph analysis.

Goat Q: A distributed message broker

goat Q, a distributed message broker explores the design and implementation of a robust message broker system. Utilizing advanced distributed concepts of network and synchronization the project aims to enhance efficiency and reliability of message delivery which fits in an event driven system. It also ensures fault tolerance and scalability. It also considers the integration with containerization and on premise and cloud deployment models to use goatQ as a message broker solution in production. The project seeks to unravel the intricate design of message brokers, illuminating the functionality of publishers, subscribers, and message queues. A key focus lies in a rigorous performance analysis, evaluating metrics such as throughput, latency, and resource use across wide variety message broker implementations. Scalability and fault tolerance, critical considerations in the realm of distributed systems, are addressed through an exploration of how message brokers adapt to dynamic scaling requirements and recover from failures. By synthesizing findings from diverse dimensions of message broker technology, this research project aims to equip technology professionals with valuable insights, aiding informed decision-making in the selection, optimization, and integration of message brokers within their ecosystems. Keyword: About four key words or phrases in alphabetical order, separated by commas. Keywords are used to retrieve documents in an information system such as an online journal or a search engine. (Mention 4-5 keywords)

The right to be forgotten: separate conceptual issues

The article is devoted to the study of the emergence and formation of the human right to be forgotten as the right of an individual to request the removal of his or her personal data from public access through search engines, under certain conditions. It is found that the establishment of the right to be forgotten is often associated with one of the key decisions of the Court of Justice of the European Union, namely, in the case of Google Spain v. Costeja Gonzalez, which has gained wide international publicity. However, it is important to note that freedom of speech and freedom of access to information are conflicting fundamental rights to the right to be forgotten. The right to privacy and the data protection regime do not exist in a vacuum: the right to privacy can often clash with other rights, in particular the right to freedom of expression, for example, in terms of censorship. The author analyses international judicial precedents regarding the acknowledgement of the right to be forgotten in the sphere of the digital human rights system, and finds that the rulings typically pertain to data that might drastically influence the fundamental rights to privacy and personal data protection. Furthermore, the courts explicitly assert their intention to achieve an equitable balance between these rights and the public's right to access information. Hence, the resolution of numerous conflicts is largely contingent on the factual context of each case. The author reviews the legal regulation of the right to be forgotten, in particular, the Regulation of the European Parliament and of the Council of 27 April 2016 (General Data Protection Regulation), the 1995 Data Protection Directive, as updated and supplemented by the above-mentioned Regulation, and the European Convention on Human Rights, etc. Although the concept of the right to be forgotten is not recognised in the Ukrainian legal system, the Law of Ukraine "On Personal Data Protection” states that deletion or destruction of personal data in the information landscape is possible upon filing a complaint or going to court.

Climate Change and Socio-Economic Impacts: Determinants of Vulnerability for Developing Countries

Climate change is the connected system of solar cycle that creates fluctuations weather arrays across tropics to polls. Anticipated climate changes for the 21st century have been encountered complex challenges for humanity that significantly influence over diverse components such as environmental, ecological, socio-political and socio-economic systems among others. This study incorporates a desk literature review and at the first step researchers shortlisted the keywords regarding climate change, socioeconomic impacts and determinants of vulnerability. Mixed method approach applied for this desk review. Numerous online search engines such as Google, Google Scholar, Scopus, Web of Science and Springer were selected to review the published research studies. The collected data comprises on various forms such as book chapters, books, research articles, reports, working papers, organizational evaluation studies and conferences papers. After strict inclusion and exclusion criteria researchers gathered to 89 studies from 31 publications outlets, which were interrelated to different search engine and covering climate change impacts on developing countries. The findings endorsed the climate change socio-economic impacts are more sever particularly in developing countries of south Asia like Pakistan. The astonishing and spatial heterogeneities are the clear indications for comprehensive integrated interventions, policies and procedure to eliminate or reduce socio-economic climate change impacts of developing countries. Keywords: Climate change, Socio-economic impacts, Determinants of vulnerability, Environmental degradation, climate change and developing countries

Rationale, completeness and quality of evidence for the use of ursodeoxycholic acid in neonatal hyperbilirubinemia

Background. Systematic reviews are considered the highest evidence of the effectiveness and safety of treatment methods used in clinical practice. The veracity of a results and conclusions of systematic reviews is directly related to their quality. The aim of the study is an assessment of the currency, completeness and methodological quality of published systematic reviews on the evaluation of the effectiveness of ursodeoxycholic acid (UDCA) for the treatment of neonatal hyperbilirubinemia. Materials and methods. A meta-epidemiological methodological study was conducted. The search for evidence sources was performed in November 2023 in the specialized databases MEDLINE, Cochrane Central Register of Controlled Trials (CENTRAL), Cochrane Database of Systematic Reviews (CDSR), LILACS, CNKI, LENS.ORG, еLibrary.Ru, in registers ClinicalTrials.gov, ICTRP, ISRCTN, PROSPERO, as well as in the Google Academy and Google search engines. Additionally, the lists of references and citations of selected publications have been reviewed. Only systematic reviews and randomized clinical trials are included in the study. The search was carried out to assess the currency and completeness of systematic reviews. A systematic review is considered currency if the most recent studies are included in its analysis. A systematic review is considered complete if its analysis includes all identified studies that meet the inclusion criteria set by the review authors and are published no later than the date of the last search conducted by the review authors. The methodological quality of the systematic reviews was assessed using the AMSTAR-2 tool. Results. As a result of the search, 4 systematic reviews and 23 randomized trials were identified. All reviews evaluated the effect of UDCA in combination with phototherapy on the level of total serum bilirubin, the duration of phototherapy and the frequency of adverse events (for example, loose stools, vomiting, rash) compared with phototherapy alone and/or placebo. All systematic reviews have been published over the past two years, but have already lost their currency. There are missing studies and/or outcomes in each review. The methodological quality of the reviews was found to be extremely low. Conclusion. Given the listed shortcomings of systematic reviews, their results and conclusions should be treated with caution. In order to obtain the most accurate and reliable evidence, a new systematic review is needed.

Rural Tourism and Homestays in India: Impact on Local Economy, Culture and Ecology

Purpose of the study: This study explores rural tourism as a sustainable form that encompasses environmental preservation, entrepreneurial opportunities, and the preservation of traditional village customs, values, and practices. Methodology: The research methodology employed a literature review approach, focusing on secondary data sources. The search utilized the Google Scholar database as a search engine, with the initial 500 results sorted by relevance to ensure comprehensive coverage of relevant scholarly sources. Finally, 31 articles were selected for this study. Principal Findings: Operating homestays can provide alternative accommodation options and catalyze the promotion of rural tourism, benefiting the local community, economy, and regional art and culture. A well-executed marketing plan in rural tourism can bring significant societal advantages by channeling resources from urban to rural areas and curbing rural-urban migration. Applications of the study: This study can be helpful in the tourism and hospitality industry. It is instrumental in promoting rural tourism and supplementary accommodation like homestays in India, thus boosting the local economy and promoting local culture and tradition. Novelty/Originality of the study: Tourism and related industries substantially impact employment due to the sector's labor-intensive nature. Village tourism can generate income and employment and contribute to rural development, preventing rural-urban migration and promoting sustainable revenue generation.

A STUDY ON IMPACT OF DIGITAL MARKETING IN BRAND AWARENESS

This study investigates the influence of digital marketing strategies on brand awareness among consumers. Through a comprehensive review of literature and empirical analysis, the study reveals the significant role played by various digital marketing channels such as social media, search engine optimization, and content marketing in enhancing brand visibility and recognition. The findings suggest that companies leveraging digital marketing effectively experience higher levels of brand awareness compared to those relying solely on traditional marketing approaches.

Induced pluripotent stem cells in cartilage tissue engineering: a literature review.

A literature search was conducted using scientific search engines, PubMed, MEDLINE, and Google Scholar databases with the terms 'Cartilage tissue engineering' and 'stem cells' to retrieve published literature on chondrogenic differentiation and tissue engineering using MSCs, ESCs, and hiPSCs. hiPSCs may provide an effective and autologous treatment for focal chondral lesions, though further research is needed to explore the potential of such technologies. This review has provided a comprehensive overview of these technologies and the potential applications for hiPSCs in regenerative medicine.

Morphological and molecular characteristics of a Trypanosoma sp. from triatomines (Triatoma rubrofasciata) in China

BackgroundTriatomines (kissing bugs) are natural vectors of trypanosomes, which are single-celled parasitic protozoans, such as Trypanosoma cruzi, T. conorhini and T. rangeli. The understanding of the transmission cycle of T. conorhini and Triatoma rubrofasciata in China is not fully known.MethodsThe parasites in the faeces and intestinal contents of the Tr. rubrofasciata were collected, and morphology indices were measured under a microscope to determine the species. DNA was extracted from the samples, and fragments of 18S rRNA, heat shock protein 70 (HSP70) and glycosomal glyceraldehyde-3-phosphate dehydrogenase (gGAPDH) were amplified and sequenced. The obtained sequences were then identified using the BLAST search engine, followed by several phylogenetic analyses. Finally, laboratory infections were conducted to test whether Tr. rubrofasciata transmit the parasite to rats (or mice) through bites. Moreover, 135 Tr. rubrofasciata samples were collected from the Guangxi region and were used in assays to investigate the prevalence of trypanosome infection.ResultsTrypanosoma sp. were found in the faeces and intestinal contents of Tr. rubrofasciata, which were collected in the Guangxi region of southern China and mostly exhibited characteristics typical of epimastigotes, such as the presence of a nucleus, a free flagellum and a kinetoplast. The body length ranged from 6.3 to 33.9 µm, the flagellum length ranged from 8.7 to 29.8 µm, the nucleus index was 0.6 and the kinetoplast length was −4.6. BLAST analysis revealed that the 18S rRNA, HSP70 and gGAPDH sequences of Trypanosoma sp. exhibited the highest degree of similarity with those of T. conorhini (99.7%, 99.0% and 99.0%, respectively) and formed a well-supported clade close to T. conorhini and T. vespertilionis but were distinct from those of T. rangeli and T. cruzi. Laboratory experiments revealed that both rats and mice developed low parasitaemia after inoculation with Trypanosoma sp. and laboratory-fed Tr. rubrofasciata became infected after feeding on trypanosome-positive rats and mice. However, the infected Tr. rubrofasciata did not transmit Trypanosoma sp. to their offspring. Moreover, our investigation revealed a high prevalence of Trypanosoma sp. infection in Tr. rubrofasciata, with up to 36.3% of specimens tested in the field being infected.ConclusionsOur study is the first to provide a solid record of T. conorhini from Tr. rubrofasciata in China with morphological and molecular evidence. This Chinese T. conorhini is unlikely to have spread through transovarial transmission in Tr. rubrofasciata, but instead, it is more likely that the parasite is transmitted between Tr. rubrofasciata and mice (or rats). However, there was a high prevalence of T. conorhini in the Tr. rubrofasciata from our collection sites and numerous human cases of Tr. rubrofasciata bites were recorded. Moreover, whether these T. conorhini strains are pathogenic to humans has not been investigated.Graphical

Telecoaching: a potential new training model for Charcot-Marie-Tooth patients: a systematic review

IntroductionCharcot–Marie–Tooth disease (CMT) is an inherited neuropathy that affects the sensory and motor nerves. It can be considered the most common neuromuscular disease, with a prevalence of 1/2500.MethodsConsidering the absence of a specific medical treatment and the benefits shown by physical activity in this population, a systematic review was completed using several search engines (Scopus, PubMed, and Web of Science) to analyze the use, effectiveness, and safety of a training program performed in telecoaching (TC). TC is a new training mode that uses mobile devices and digital technology to ensure remote access to training.ResultsOf the 382 studies identified, only 7 met the inclusion criteria. The effects of a TC training program included improvements in strength, cardiovascular ability, and functional abilities, as well as gait and fatigue. However, the quality of the studies was moderate, the size of the participants in each study was small, and the outcome measured was partial.DiscussionAlthough many studies have identified statistically significant changes following the administration of the TC training protocol, further studies are needed, with appropriate study power, better quality, and a higher sample size.

Perceptions, attitudes, and behaviors among adolescents living with obesity, caregivers, and healthcare professionals in Italy: the ACTION Teens study

PurposeACTION Teens (NCT05013359) was conducted in 10 countries to identify perceptions, attitudes, behaviors, and barriers to effective obesity care among adolescents living with obesity (ALwO), caregivers of ALwO, and healthcare professionals (HCPs). Here, we report data from participants in Italy.MethodsThe ACTION Teens cross-sectional online survey was completed by 649 ALwO (aged 12– < 18 years), 455 caregivers, and 252 HCPs in Italy in 2021.ResultsMost ALwO thought their weight was above normal (69%), worried about weight affecting their future health (87%), and reported making a weight-loss attempt in the past year (60%); fewer caregivers responded similarly regarding their child (46%, 72%, and 33%, respectively). In addition, 49% of caregivers believed their child would lose excess weight with age. ALwO (38%) and caregivers (30%) most often selected wanting to be more fit/in better shape as a weight-loss motivator for ALwO; HCPs most often selected improved social life/popularity (73%). ALwO (25%) and caregivers (22%) most frequently selected lack of hunger control and not liking exercise, respectively, as weight-loss barriers, while HCPs most often agreed that unhealthy eating habits were a barrier (93%). ALwO most often obtained weight-management information from family/friends (25%) and search engines (24%); caregivers most often obtained information from doctors (29%).ConclusionIn Italy, the impact of obesity on ALwO was underestimated by caregivers, and ALwO and HCPs had different perceptions of key weight-loss motivators and barriers. Additionally, the internet was a key information source for ALwO, which suggests new education/communication strategies are needed.Level of evidenceIV; Evidence obtained from multiple time series with/without intervention, e.g. case studies.Trial Registration: ClinicalTrials.gov, NCT05013359.

Analysis of the most popular online BAC calculators = Analiza najpopularniejszych dostępnych w sieci „kalkulatorów trzeźwości”

In order to check their sobriety after drinking alcohol, drivers can use applications available online that perform prospective estimation of alcohol content, called ‘alcomat online’ or ‘BA C calculators’. The aim of the study was to analyse the method of performing calculations using ‘BA C calculators’ available on the Internet and to assess their reliability. The five most popular ‘calculators’ found in the Google search engine and a commercial one were analysed. The applications were tested by entering data on 10 cases of alcohol consumption by people were tested for alcohol content in exhaled air using the Alcotest 7510 analyser and alcohol curves were plotted for them. Then, real ethanol concentrations and complete ethanol elimination times for these people were compared with values calculated by the applications. The analysed ‘calculators’ base their calculations on various principles. Both the maximum alcohol concentrations and the time of their occurrence varied among the applications, but all seem to use the alcohol distribution coefficient established by Widmark. The use of individual elimination rates ranging from 0.12 to even 0.3‰/h was also observed. The time for complete alcohol elimination indicated by the applications was in most cases longer than the actual time. Online applications such as the ‘BA C calculator’ available to Polish users may be helpful tools for determining the time of complete elimination of alcohol from the body. However, due to the different calculation methods used in applications, which sometimes lead to different conclusions, they should be approached with great caution. These applications will not replace reliable sobriety tests, e.g. analysis of exhaled air.